Whole-Cell Liquid Biopsy

Comprehensive Tumor Mutational Profiling From Whole Cancer Cells

Unlike ctDNA tests, CellSight™ DNA analyzes intact circulating tumor cells. One blood draw gives you the genomic profile and the cells it came from.

An oncologist reviews results on a tablet with a patient

517

Genes profiled from intact tumor cells

>99%

Analytical sensitivity for single nucleotide variants

10 to 14

Days from specimen receipt to report

CLIA

Certified laboratory, Jupiter, Florida

Built for the Decisions You Make

CellSight™ DNA is designed for oncologists who need genomic answers when tissue is limited, exhausted or too risky to obtain again.

At Diagnosis

Genomic profiling from blood when tissue is scarce, inaccessible or slow to process. 517 genes with MSI and TMB, in 10 to 14 days.

At Progression

Detect resistance mutations to guide the next therapy with fewer repeat invasive procedures.

When Tissue Biopsy Isn't Feasible

A noninvasive route to genomic information for patients with high-risk comorbidities or deep tumor sites.

Why Whole Cells Matter

Cell-free DNA is a mixture of short, degraded fragments shed by tumor cells, normal cells and blood cells. A circulating tumor cell is the tumor itself, intact and in circulation.

Analyzing intact cancer cells preserves tumor context, captures heterogeneity and keeps the complete genetic material together. Each variant is called from tumor-derived DNA rather than inferred from a dilute fraction, which supports clearer interpretation of copy number changes and tumor mutational burden.

We report CTC counts for every accession alongside the genomic findings, giving you a view of tumor cells in circulation at the time of the draw.

CellSight™ DNA Capabilities

Every result is built on validated outputs. We do not report what we have not validated.

Whole Cancer Cell Isolation

Proprietary, patent-pending enrichment captures rare tumor cells, including in low-burden patients, with CTC counts reported for the full accession.

Genomic Profiling

Next-generation sequencing of 517 cancer-relevant genes: SNVs, indels and copy number variants, plus TMB and MSI status.

Serial Monitoring

Noninvasive and repeatable. Compare CTC counts and genomic findings across time points without another biopsy.

Our Process

A standard specimen workflow with a dedicated preservation tube. Results are typically returned in 10 to 14 days from specimen receipt.

  1. Sample Collection

    Two 10 mL CellSave CTC Preservation Tubes of peripheral whole blood, supplied in the CellSight™ DNA kit.

  2. Whole Cancer Cell Isolation

    Circulating tumor cells are enriched by negative selection using our proprietary isolation method.

  3. Cell Identification

    Candidate tumor cells are identified and enumerated for the accession.

  4. Genomic Profiling

    DNA from the isolated cells is sequenced across the panel.

  5. Reporting

    A clear, structured clinical report with SNVs, indels, CNVs, TMB, MSI and CTC count, delivered through the Client Portal in 10 to 14 days.

  6. Next Steps

    Findings support therapy selection, monitoring at progression and clinical trial enrollment.

CellSight DNA workflow: blood draw, whole cell isolation, cell identification, sequencing, report Blood draw Peripheral whole blood Whole cell isolation Negative selection removes blood cells Cell identification CTCs confirmed and counted Sequencing 517-gene NGS panel Report SNVs, indels, CNVs, TMB, MSI, CTC count WHOLE CELLS, NOT FRAGMENTS 10 TO 14 DAYS

Supporting patients and the providers who care for them

Providers get decision-grade genomic information when tissue is scarce. Patients get answers from a blood draw instead of another procedure.

See What a CellSight™ DNA Report Looks Like